Here are 10 common medications (or medication classes) that can cause loss of balance, dizziness, or unsteadiness, especially when first starting them or with higher doses:
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Benzodiazepines
Examples: alprazolam (Xanax), lorazepam (Ativan)
→ Can slow reaction time and coordination. -
Opioid pain medications
Examples: morphine, oxycodone, hydrocodone
→ Can cause dizziness, sedation, and poor balance. -
Antidepressants (especially TCAs and some SSRIs)
Examples: amitriptyline, sertraline
→ May cause dizziness or lightheadedness. -
Antipsychotics
Examples: risperidone, quetiapine
→ Can affect movement control and cause sedation. -
Blood pressure medications
Examples: beta blockers (metoprolol), ACE inhibitors (lisinopril)
→ Can cause drops in blood pressure leading to dizziness when standing. -
Diuretics (water pills)
Examples: furosemide, hydrochlorothiazide
→ Can cause dehydration or electrolyte imbalance affecting balance. -
Antihistamines (especially older ones)
Examples: diphenhydramine (Benadryl), chlorpheniramine
→ Can cause drowsiness and impaired coordination. -
Anti-seizure medications
Examples: phenytoin, carbamazepine
→ Commonly cause dizziness or unsteady walking. -
Muscle relaxants
Examples: cyclobenzaprine, baclofen
→ Can impair coordination and cause sedation. -
Medications for vertigo or nausea
Examples: meclizine, scopolamine
→ Can worsen balance or cause drowsiness.
Important notes
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Loss of balance is more likely in older adults, but it can happen at any age.
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Combining medications or taking them with alcohol greatly increases the risk.
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Sudden or severe balance problems should be checked by a healthcare professional.